Endocrine Abstracts

Background: Thyroid volume correlates positively with body mass index (BMI). This correlation holds true for both iodine-sufficient and mild/moderate iodine-deficient areas. We examined the association between thyroid volume and BMI and change in BMI over 4 years in middle-age adults recruited from the general population.Methods: A total of 2495 subjects, for whom thyroid volume, FT4 and TSH were available (women aged 35–60 years and men ...

Introduction: The question if obesity may protect against osteoporosis is still a matter of discussion. A breakthrough in this debate may be the introduction of a state-of-the-art densitometric software (CoreScan) suitable for fast and accurate volumetry of total body fat (BF), including android (A), female-type (F) and visceral fat (VAT) volumes.Aim: The aim of the study was to analyze an association between bone mineral density (BMD]), concentrations o...

Purpose: Thyroid autoimmune diseases occur more frequently in women than men. A previous study reveals that exogenous testosterone may have a protective effect on thyroid autoimmunity in men with Hashimoto’s thyroiditis. But no study has determined whether sex hormones produce any effect on thyroid antibody titreş in women. The primary study aim was to assess whether exogenous testosterone affects thyroid autoimmunity in trans-men with increasing testosterone levels....

Introduction: Serum 25(OH) vitamin D levels are shown to be significantly lower and associated with lower remission rates in Graves disease. In this study we aimed to investigate the impact of baseline vitamin D levels on thyroid volume in patients with new-onset Graves disease.Materials and methods: This is a monocenter cross sectional study with a total of 61 new-onset Graves disease patients (n:61, F: 40, M:21) who were divided into two groups accordi...

Introduction: The study describes volume changes of thyroid gland in patients with Graves’disease (GD) after radioactive iodine treatment in the University hospital in Hradec Kralove.Patients and Methods: Retrospectively, we analyzed 66 patients with GD (57 women and 9 men, mean age 52 ± 13.4 years). Volume of thyroid gland was measured before and 1 year after application of radioactive iodine.Results: Total decrease of ...

It has previously been shown that protein restriction during pregnancy impairs the physiological adaption to pregnancy by reducing plasma volume expansion. This may mediate the effects of maternal diet on placental and fetal development. This study investigated the mechanisms by which maternal diet interacts with plasma volume expansion.Female Wistar rats were mated and fed a control (18%, n=32) or low protein (9%, n=32) diet during pregnan...

IntroductionIn primary hyperparathyroidism (PHPT) the chronic overproduction of parathormone (PTH) is mostly due to a solitary adenoma.AimThe aim of our study was to examine the relationship between calcium-phosphate metabolism and the volume of the parathyroid adenoma (PTA) in patients with PHPT.Material and methodsThe study included 195 patients with biochemical...

Background: Ultrasound guided minimally invasive therapies are becoming increasingly popular for the treatment of symptomatic benign thyroid nodules. Efforts have been directed on the prediction of volume reduction as a measure of efficacy of the procedure. Aim of the present study is to identify predictors of 6-months volume reduction rate (VRR) after radiofrequency ablation of benign thyroid nodules.Materials and Methods: We performed a retrospective s...

Introduction: Smoking habit has always been considered to exert a detrimental effect on male reproductive health. However, several studies do not clearly demonstrate a negative effect of smoke on semen parameters. In addition, the effect of smoke on male genital tract has been poorly studied by ultrasound (US). We evaluated the correlations of smoking with seminal and US characteristics in males of infertile couples. Methods. A consecutive series of 426 men was systematically ...

Suppressive therapy with thyroxine is the standard conservative treatment for solitary benign thyroid nodules. However, factors which may influence the response to treatment remains controversal, as well as the risc of thyroxine administration.We prospectively evaluated the effects of twelve months thyroid-stimulating hormone suppression with Levothyroxine (L-T4) in reducing the volume of benign solitary nodules, and the effects of reduced...